Parallel Dapsone and Rifampicin Resistance: A Prospective Study
نویسندگان
چکیده
منابع مشابه
Survey for secondary dapsone and rifampicin resistance in Cuba.
A total of 1211 Cuban multibacillary leprosy patients treated for at least 5 years were clinically and bacteriologically examined. They were being treated according to a 2-phase monotherapy regimen with RMP first and DADDS afterwards. On skin-smear examination 50 patients were found positive, of which 9 showed a BI of 3+ or higher at any site. With regard to the clinical status the only cases f...
متن کاملStudy of rifampicin resistance and comparison of dapsone resistance of M. leprae in pre- and post-MDT era.
The aim of this study to study the drug resistance patterns of dapsone (pre- and post-MDT) and rifampicin (post-MDT era). All the 84 patients from pre-MDT period (1985-1990) and 77 patients for post-MDT period (1990-2002) reporting to a tertiary care hospital-NJIL & OMD, Agra and referred for drug susceptibility testing were included in the study. Drug resistance was studied by mouse foot pad m...
متن کاملTreatment of paucibacillary leprosy patients with dapsone and rifampicin.
Dapsone resistance is found worldwide (1,2) and resistance to other available drugs such as clofazamine (3) and rifampicin (4) also occurs. It is known that paucibacillary leprosy patients harbour <106 bacilli (5). However, the treatment of paucibacillary leprosy is of long duration. It is psychologically undesirable for a symptom-free, paucibacillary patient to receive therapy for a long perio...
متن کاملPrimary dapsone resistance in China.
Ninety-seven strains of Mycobacterium leprae recovered from patients with previously untreated multibacillary leprosy were tested for dapsone susceptibility. The specimens originated from Shanghai Municipality, Jiang-su Province and Fu-jian Province. Approximately 28% of the strains either did not infect the mice or the results of susceptibility were inconclusive due to the low proportion of vi...
متن کاملScreening for HIV-Associated Tuberculosis and Rifampicin Resistance before Antiretroviral Therapy Using the Xpert MTB/RIF Assay: A Prospective Study
BACKGROUND The World Health Organization has endorsed the Xpert MTB/RIF assay for investigation of patients suspected of having tuberculosis (TB). However, its utility for routine TB screening and detection of rifampicin resistance among HIV-infected patients with advanced immunodeficiency enrolling in antiretroviral therapy (ART) services is unknown. METHODS AND FINDINGS Consecutive adult HI...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese journal of leprosy
سال: 1984
ISSN: 0386-3980,2185-1360
DOI: 10.5025/hansen1977.53.28